Hours that they took down so this was how does ever making work they brought it down sent me a message that hey you have violated their terms and conditions but they’re not going to give me a strike yet because i may not know that it is bad to
Talk about avermetin then they took down this one avermectin dose and sent me the same message then they took down um this year 32 questions yesterday i appealed and of course they rejected the appeal with that they simply said we’re not gonna we are removing the
Strike for now but don’t do this again so this is one second thing that i did over the weekend i went to san francisco and so on the way back this was the uh 280 a freeway and at this place i took a picture my wife was driving so i took a
Picture and then i came back and i i painted it the title is 280 to home so with that now let’s start i think you will really be excited you’ll be it is so much interesting to see today’s topic let me give a prelude to the topic we have been talking about the
Clotting possibly because of the vaccines it would i would never forget about this because when i had started talking about it i got so much hate i got so many threats i got so many people becoming upset even to the point of that i somehow hate uk because the astrazeneca and
And the oxford is from uk and i am colluding with german scientists there was just crazy stuff but uh i had this theory at that time as well even for the doctor here in florida who died after the modernist vaccine and clotting my theory was that this is
Antibody driven and not spike protein driven and here is a an article that actually shows not only exactly how clotting occurs but it shows the exact amino acids involved in clotting i have never seen before for this clotting mechanism such a focused view of the mechanism
It almost looks like you take a little helicopter you sit in it and you land on a platelet and you see the exact mechanism that is happening they have some pretty pretty excited about this one there is another important thing to note here and that is that this is this is manageable
If we understand how does it occur then it can be managed and the management happening which remember even i have been talking about about it that heparin is not is contraindicated they actually proved that it is possible that happening will actually be useful so i will discuss how does that
Mechanism work so this is the talk let’s start our discussion the links are here so the links are this is dr bean.com one more thing as youtube started bringing us down right and left uh people asked me to move to odesi odesi’s team they are they’re so wonderful they reached
Out and they said hey we can actually copy every piece of content from youtube over to odyssey and you don’t have to do anything we will do all the work they had simply asked me to make sure that this banner and the picture and those things are correct so i’m working on
That but this is odesi so here on odaysi.com there is dr mubeen sayer then if you go there they have even i was astonished a few minutes ago i looked at it and they have copied over majority of the the videos from youtube and they’re in contact with me over
Twitter continuously discussing and they are saying that they would even support me to go live using odac so we’ll see how does that work so that is a good news that is odesi This is the article i have the pdf for the article here as well then there are some supporting links here again if you do not like wikipedia just take these topics and and and study them from wherever you feel more confident and and trusting so with this there is this alpha granule
Of the platelet what is heparin what is heparin-induced thrombocytopenia because this vaccine-induced thrombo thrombotic thrombocytopenia is very similar to heparin-induced thrombocytopenia so we will look at their comparison to each other as well and then finally this is a list of amino acids and they’re single letter codes amino acids as you know are
The bricks with which our proteins are made these are the smallest bricks with which we are made and there are a few of them i think 20 or so and there are many amino acids but 20 are the ones that are part participant in us and there are these letter numbers
Not numbers letters that represent them and we need to see this table because we look at the exact amino acids that are participating in clotting so i’m going to close this as well all of these references are present in the discussion in the links description so let’s start
Study summary so if you just wanted to know what are they saying the summary is the following they are saying for the first time so the study’s own status it is a peer-reviewed study it has been accepted and nature is a good publication engine so it is accepted in a good one
So they talk about this rare side effect of vaccine and remember the german scientists had called it that they proposed this mechanism to say this term to say we should call it vaccine induced thrombocytopenic from thrombotic thrombocytopenia and it became a huge issue that this is all political and geopolitical and all
That so now i think it is correct and we look at the mechanism to see how does this happen it resembles heparin-induced thrombocytopenia which is known for a long time in majority of the patients who are unhappy patients who are on heparin they sometimes get the hit or hepatin-induced thrombocytopenia but thrombohabrin
Induced thrombocytopenium primarily occur in patients on heparin this particular vaccine-induced thrombocytopenia or thrombotic thrombocytopenia occurs without heparin so if you are on heparin it is nothing to do with heparin it is independent of it and number two it is actually possible that if somebody is on heparin that would help alleviate
The situation or reduce the intensity of the situation now what are the results what did they find again we are still in the summary they found that platelet factor four that i’ve been discussing for a long time platelet factor four does have us have a epitope on it to which antibodies generated
Against the spike protein on the by the vaccine those antibodies cross react with the epitope on platelet factor four which in turn causes the activation of platelets which in turn causes the aggregation of platelet that is called thrombosis when the aggregation of platelet occurs when the platelets start hugging each other
And they start clotting then the amount of platelets is reduced in the body and that is thrombocytopenia so this is thrombotic thrombocytopenia this is the summary of it it is very similar to happening like uh heparin-induced thrombocytopenia and not only similar it actually attacks the antibody attacks half of the same site as
Is attacked by the hit or heparin-induced thrombocytopenia so that is a summary what is the solution to this of course anti-clotting heparin can actually be useful actually better useful than other blood thinners and i’ll explain why this is a summary of it let’s look at the mechanisms now fascinating mechanisms i really really
Appreciate these researchers so let’s start from here first of all let’s understand what is heparin-induced thrombocytopenia here is a platelet a platelet does not have a nucleus it is actually formed it is pinched off it is broken off from a bigger cell that is called megakaryocyte megakaryocytes are found in bone marrow
And smaller pieces of them are pinched off and separated and these smaller pieces are called platelets platelets have a bunch of things in them for example they have mitochondria they have alpha granules and they have dense granules as well alpha granules and dense granules are nothing but small
Purses small pockets in which enzymes are sitting if i take an alpha granule out of a platelet and look at it a little more closely in the alpha granule in that little pocket there is platelet factor four this red one that is the the protein that we’re going to talk about today
In addition to that there is insulin-like growth factor there is platelet-derived growth factor there are other clotting factors there is tumor growth factor beta and so on remember platelets function is towards clotting so of course clotting factors there is not something unusual so this is within the platelet now what happens is
Imagine this is platelet factor 4. if i go back here platelet factor 4 was present in the alpha granules alpha granules are present inside the platelet so platelets have inside of them a small pocket thousands of such pockets that pocket has this platelet factor four platelet factor four here this red block
Is also called chemokine ligand four cxcl4 why is it called a chemokine when a platelet releases this when a platelet becomes active it opens up its pockets and gives the money out to everyone to say come work with me and do clotting so when it gives the money out one part of that
Money one chemical that is released is this platelet factor four it is a chemokine factor that means it attracts more platelets there it attracts more immune system cells there it helps generate inflammation and clotting at that place where it is present normally platelet factor 4 is present in
The vicinity of platelets because it is released by the platelets this is why when the platelet factor four is attacked by the antibodies these would settle on platelets because the nearby cells or not cells these tiny things in nucleated cells let’s say the nearby cells are platelets so whatever is
Nearby is going to get attacked as well so this is the platelet factor 4. now if you add heparin in the system heparin binds with the platelet factor 4 and it does its function it is anti-clotting but in some people in some people now check out here
This is happening the one that i’m doing blue now making blue when heparine binds with the platelet factor 4 then a new epitope is formed this is just like this that if you look at my head right now imagine this is a pattern of my head and if i take this little
Thing and put it on my head now the pattern of my head is different and imagine if somebody remembers this pattern as an enemy’s pattern then that somebody is going to attack me although i am not the enemy this was just an accidental thing that this pattern was formed so
Here what happens is heparin actually binds to the platelet factor 4 in almost all of us when we have heparin however in some people when heparine and platelet factor 4 combine that give gives rise to a neo epitope epitope is an area where an antibody can bind normally anywhere from
Seven amino acids to 11 amino acids or if an amino acid is a brick from seven bricks to 11 bricks in some people when heparin binds this neo epitope becomes a target for the antibodies now the question is why and do we know who
So the answer to do we know who we do not why just like allergies that some people’s b cells generate antibodies against those happens or those epitopes to which majority of the population does not create antibodies it is a genetic structure plus result of the somatic hypermutation what is that
When our b cells are formed in us they are asked to make their own binding sites and those binding sites are made by random changes in them and in some people unfortunately a random binding site becomes created that can look at this part of heparin and platelet factor 4
Together and say well i’m going to attack this thing i don’t like it so because of that it is called a neo-epitope new epitope so here this is we’re still talking about heparin so because of heparin’s attachment to platelet factor four some antibodies which were not normally going to attack platelet factor four
Now started to bind with this with this complex then what happens so please remember these antibodies are usually idt type that means they can live for a longer period of time now then what happens once these antibodies are produced usually between five days and onwards up to 28 days
Once they are produced they usually start producing on the fifth day they continue to be formed for three months and good news after three months they go away compared to antibodies against other pathogens or pathogens or compared to antibodies generated by the b memory cells fortunately these memory cells are not formed
So antibodies are produced at the active time of heparin introduction and then within 2-3 months these antibodies are cleared out that is a good news otherwise if these antibodies were not cleared out or if the platelet sorry those b cells that are producing these antibodies these were not cleared out
Then we’ll continue to make antibodies forever then this person would never come out of the bleeding disorder so that fortunately does not happen and that is the same situation with the vaccines as well so that is it entirely a lucky thing so mechanism of clotting so now let’s say those
Platelet factor 4 and heparin combined creates an epitope against which antibodies are produced how does that cause clotting so see here let’s say this is a platelet on the surface of the platelet we have receptors to bind with the antibodies so these receptors are called if you see here fc gamma 2 a
Fc fraction constant or fraction crystalline gamma which is for igg igg antibodies called gamma antibodies and 2a is just a receptor classification and it’s a receptor what does this mean simply it means it’s a receptor on the platelet that can bind with the antibody that is against a platelet factor four or igg
So here if you see this is an antibody that has bound to platelet factor 4 and heparin and because this antibody was in the vicinity of platelet because platelet factor 4 is in the vicinity of platelet this antibody bound to the platelet once it binds to the plate so there were
Other happy platelets sitting there as well just kind of looking at what is going on here so once that binding occurs there is intense activation of a platelet so once the binding once the antibody binds on the surface of a platelet platelet becomes very angry it takes
That as a signal to become activated just like it is a signal for mast cells to become activated it is a signal for macrophages to become activated it is a normal behavior of our immune system so as soon as the platelets are bound by these antibodies they start degranulating platelets
Here degranulation will mean they would release a lot of prostaglandin they would release a lot of clotting factors we just looked at some of those things in the beginning of this talk in addition to that they would release cytokines that would activate monocytes remember these platelet factor 4 for
Example is a chemokine it’s going to attract the monocytes and other immune cells then the other cytokines in the vicinity is are going to activate those immune cells so the monocytes would come in and they would become active as well so now in that blood vessel where there is platelet clotting going
On there is inflammation going on as well this is not because of the spike protein attaching to ace2 it is the spike protein causing the production of antibodies antibodies combining with the platelet factor 4 platelet factor 4 and antibody complex sitting on the surface of the platelet activating the platelet which in turn
Then causes clotting so now still continuing why the clotting fine we now know that platelets are active when platelets are active they start holding each other they start binding with each other because they know their function is to clot so an active platelet not only cause our means to
Come in that area to work they would also start clotting with each other so that is one reason clotting would start a second reason is this platelet factor four this protein that was released by platelets when it is bound with the antibodies which antibodies the antibodies that are
Generated because of the vaccine or because of heparin once those antibodies are bound to platelet factor four platelet factor four has a conformational change in it what does that mean once you unlock the door you can open the door so moving the door in or out to open it
Is a conformational change or you may have seen the older movies not older movies the um what are those movies where people go and do treasure hunting and stuff so you may have seen movies where there is an old temple and somebody goes in and
Moves a knob and then there are 20 gears that move and then another thing moves or a wall moves these kind of things are called conformational changes so when the antibody is attached to platelet factor 4. there is a conformational change in the platelet factor 4 and big blobs of carbohydrates
Specifically negatively charged carbohydrates get attached to the platelet factor four when they get attached to the platelet factor four see here in the middle they start aggregating the factor fours together factor four were sitting in the blood vessel all floating around like fish and now we have an antibody attached to them
That caused a big carbohydrate to become attached to them sugar attached to them then those sugars attached to each other that brought platelet factor forced together that blood brought the platelet to which these factor fours and antibody complexes are attached all of them together that also caused clotting so two mechanism platelet themselves
Becoming active because antibody complex sat on them and the active platelet are going to aggregate with each other so that is one mechanism of clotting the second mechanism of clotting is that these platelet factor fours are now aggregating with each other because of big and ionic polysaccharides or carbohydrates which
In turn bring these platelets together as well because these silly pritlet are stuck to them with antibodies where did these antibodies come from these are the ones that are produced against a vaccine or heparin so that clustering would be clotting now in the study what did they do
In the study they took samples of the patients who were having who were suffering with clotting after vaccine so they took five samples of patients who had received astrazeneca and developed clotting the age was 35 to 72 years mean age was 44 year 40 were women 60 were men
So the concept of women under the 50 years of age here 40 for women the rest were men they had gotten the vaccine they had developed the clotting so what happened was if we now look at the mechanism they got the vaccine vaccine produced these spikes or not just a spike maybe
It was the adenovirus remember this is happening mainly in adenovirus based but it is also happening in the messenger rna so it may be the spike or it may be the adrenal virus or maybe both of them do it the end result was b cells will produce antibodies that is
What we want them to do these antibodies If incorrectly bind to plate uh platelet factor four which will happen in some people who we do not know when the antibody will bind with the platelet factor four what they found was researchers it did not need heparin to be present to create a new epitope this this antibody produced
Because of a vaccine was independently able to connect with the platelet factor 4 without any other help fortunately in very smaller number of people otherwise if it was happening to a larger number of people then everybody would be getting in trouble now my conjecture is that it is because of adenovirus because
Adenovirus based vaccine are known to cause clotting for decades ago it’s not a new phenomena i know that scientists lead us to believe it is somehow a new thing it’s not new it is known so from there my hypothesis is more than the spike it may be
Adenoviruses this is why this issue is occurring more in adenovirus based vaccines but we have seen this with messenger rna as well so maybe maybe spike protein is also doing this so here no heparin is needed antibodies would connect with the platelet factor four and all the remaining mechanism that we
Just discussed would become active without the need for heparin and they saw that this occurrence was 14 to 40 days mean was 28 days this also goes against the message that was given by forty who said from three days to seventeen days and mean is nine days i heard an interview
In which he was saying that so again i can give him a to be fair to him he didn’t know but hopefully he would correct his message now it can be from 14 days to 40 days mean 28 days and we have seen it starting to occur in five days as well now
How did they find out exactly where the antibody was attaching they not only found the antibodies are attaching and causing clotting they actually found exactly where on the platelet factor for these were attaching that is such a beautiful thing they did so here is what they did fortunately once again platelet factor 4
Is a small protein it’s not a very big protein i think it is 70 amino acids long so not a big protein they created 70 versions of this protein and in every version in every mutation they changed one amino acid at a time so they had 70
70 versions of this platelet factor 4 and every version had a single amino acid modified and was different from others then they took the antibodies present in the patients of the vaccine-induced clotting and they put those antibodies on these versions of the platelet factor four and they saw where the antibody attacks
More versus less based on that they could focus on the area of the platelet factor four where the antibodies were attacking this is beautiful i would love to go and shake their hands for the work they did and this is genius so what they found was the following
If you see here this is the platelet factor four in this factor four this is an area where heparin connects and the heparin induced thrombotic thrombocytopenia or thrombocytopenia antibodies connect they found out that vaccine induced thrombosis thrombotic thrombocytopenia antibodies were binding so remember the antibody binds to an epitope that is anywhere
From seven eight amino acids to eleven it was binding to eight amino acids and four of them were common with heparin-induced thrombosis amino acid four of them were independent so part of it was common and part of it was independent so you might say so what
Why is mobine talking about this in such depth one it is so much fun to look at how much they know secondly this tells us if heparin is given to a patient of this clotting then heparin is going to come here and bind with this area and displace the
Antibodies that are attached here so heparin would not only help with the blood thinning it would help to displace the incorrectly bound antibodies so heparin at least from this paper’s point of view becomes a better solution for clotting than other anti-clotting factors remember even i had been saying
Don’t give heparin because that might cause hit as well so now the hit is still possible but heparin seems to be actually a better choice and i’ll show you all of this in the paper so four amino acids unique four amino acids with heparin or common with heparin
Which allows happening to come displace these antibodies also we just talked about it heparin so let’s say this is the vaccine-induced antibody connected here to this area then you give heparin heparin would come and bind here and displace this antibody and help reduce clotting we just talked about it second mechanism this is
The beauty of this whole paper they actually found the exact amino acids that were involved in making the epitope they found this if you look at me my picture in the side they found the exact pattern to which the antibodies were attacking that that is a beautiful thing
So this is not a hypothesis anymore this is not a conjecture this is not we think this may be they actually came back with the exact amino acids so let’s see those amino acids and i’ll explain this diagram here is their table so if i go to the bottom of this paper
They have a table a over here i think i scrolled too much so give me a second here so look at this this table these are the eight amino acids one two three four five six seven eight eight amino acids and these are the positions the 22 means the position number 22 then
Position number 23 28 46 47 and the beginning r or h is the letter for the amino acid that was originally there and then they had changed it to a known amino acid and then did their experiments to find out these amino acids were involved in making the
Epitope how are they involved so look at it this is this is beautiful so amino acid at place 22. that amino acid is arginine then at 23 is histidine at 28 is glutamate 46 is lysine 47 is arginine then all the other 50 62 and 66 these
Are all lysine as well so how many lysines one two three four four lysines one arginine actually two arginines one glutamate and one histidine these were the and they know the exact placement of these amino acids exact placement of these bricks now you can say that here these bricks are
Pretty separately present why are they making an epitope remember that these ropes these proteins are folded when they’re folded various parts of them which may be on a line far away from each other but when they’re folded they’re brought together to make combined areas so when this protein is
Folded the 3d shape may have all of those come together that becomes the epitope so how is that look like they actually have a picture of it here this look at this picture this one which which says vaccine induced thrombotic thrombocytopenia and equals five here these red ones are the amino acids
That i just showed you and this is a globular folded platelet factor four and the antibody binds here look at the heparin on the b side heparin binds to a very similar area there is just four amino acid now this is let’s say from the other side
From the back side of this platelet factor four and you can see some amino acid here are different from the happening so there is a there is a common part of the antibody attack by vaccine or by happening induced antibodies and there is a dissimilar part as well
So then if you read this paper in in here you would actually see we identified eight surface amino acids that were necessary for binding of vaccine induced thrombo thrombotic thrombocytopenia samples and then they talk about those amino acids then they talk about the mechanism that i just
Discussed as well there is also an interesting thing here our results explain why some vitt samples tested in studies by schultz et all and greeny green acre remember they were the original scientists who said this is vaccine were inhibited by therapeutic doses of heparin so this is the discussion um
I think it is a beautiful mechanism there are some not only the beauty of the mechanism itself is interesting what is important is it is because of the antibodies that means i have been saying for a long time that cardiac inflammation is going to be an antibody based thing as well i
Am sure that we will see that to be correct as well the reason is that these mechanisms have been observed before we haven’t seen these things specific only to coronaviruses so those folks who continue to this is at the end just my little disagreement with some other researchers or scientists not
Researchers or doctors who just keep saying this is the spike protein causing clotting this is a spike protein causing inflammation it is not that it still may be spike protein caused generation of antibodies so of course no vaccine no clotting so vaccine did something it the clotting
Is coming from there so i’m not saying vaccine is not the cause here what i’m saying is when we take an incorrect mechanism then people just dismiss us because they know the mechanism is incorrect the correct mechanism is immune systems response then fortunately this can be tackled with heparin
Secondly if we can provide support to the patient patient will become okay within two three months because after that these antibodies are gone no memory b cells are formed so we are patient is actually lucky and similarly i feel that for cardiac inflammation it will be antibody dependent inflammation compared to spike protein
Going and attacking the heart so That is a discussion i’m gonna um stop here we’ll do a little chit chat as well my brother is visiting me from tomorrow for a few days so we are doing some preparations and cooking and those so i may have a smaller period of time for a chit chat but um
I’m going to come back for the chit chat there is there are some questions can you please hold on to your questions and uh come back so for example jody says can we just take prednisone for this my son and i have both gotten this mild version randomly in past probably
Viral and pretty swollen work yes you can because prednisone at the end of the day would suppress immune system the only thing is if you suppress the immune system too much that can reduce the efficacy of the vaccine but i would rather have a vaccines efficacy reduced compared to
People developing clotting and dying And another thing is there could be aspirin or other anti-clottings as well so lizzy says it’s the immune system response to vaccine and to the virus in natural infection yes so in the natural infection this can happen as well and in that case as well it may be the clotting
Because of antibodies or it could be because of inflammation causing clotting their mechanism can be very different because the virus causes such a widespread inflammatory response that clotting is bound to occur and i’ve discussed those mechanisms before okay so let’s stop and i’m gonna come back again for a few minutes
In a few minutes and we’ll do a chit chat and sorry i forgot to say please like subscribe and share and there are some links in the description if you would like to support this work after the youtube’s continuously demonetization and removal of the videos i think it is
Becoming more and more important to support but anyways totally up to you if you wanted to support there are three links one is with paypal other one is buy me a coffee that doesn’t need paypal and then there is a patreon as well thank you and i will see you in a few
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